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MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1, Pages 72-80 doi: 10.15302/J-FASE-2016089

Abstract: By using the TOPFlash system we demonstrated that miR-148b could activate Wnt/β-catenin pathway andThese results were considered to indicate that miR-148b could activate the Wnt/β-catenin signal pathway

Keywords： miR-148b hair follicle proliferation NFAT5i> Wnt10bi>

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NES1i>/KLK10i> and hNISi> gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Frontiers of Medicine 2019, Volume 13, Issue 6, Pages 646-657 doi: 10.1007/s11684-018-0643-y

Abstract: , we supposed to have an “enhanced firepower” effect by combining overexpressed gene therapy and Itomography/computed tomography (micro-PET/CT) imaging showed that the combined gene therapy and Ithat via inhibition of expression, overexpressed might enhance the effect of radiation therapy of I

Keywords： androgen-independent prostate cancer normal epithelial cell-specific 1/kallikrein 10 sodium/iodide symporter

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NO hydrogenation to NH over FeCu/TiO catalyst with improved activity

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12, Pages 1973-1985 doi: 10.1007/s11705-023-2364-2

Abstract: Notably, the optimized 10Fe-8Cu/TiO₂ catalyst exhibited exceptional catalytic performanceWe employed in situi> diffuse reflectance Fourier transform infrared spectroscopy and conducted

Keywords： NO hydrogenation synthetic ammonia 10Fe-xi>Cu/TiO₂ high selectivity

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Discovery of Kaempferol, a Novel ADAM10 Inhibitor, as a Potential Treatment for Staphylococcus aureusi> Infection Article

Tingting Wang, Jianfeng Wang, Xiangzhu Xu, Fan Jiang, Hongfa Lv, Qinghui Qi, Can Zhang, Qianghua Lv, Xuming Deng

Engineering 2023, Volume 28, Issue 9, Pages 206-221 doi: 10.1016/j.eng.2023.03.006

Abstract: indispensable specific cellular receptor for α-toxin (Hla), a-disintegrin and metalloproteinase 10(ADAM10) is exploited to accelerate S. aureus infection through diverse mechanisms.The extraordinary contribution of ADAM10 to S. aureus pathogenesis renders it an attractiveOur study is the first to demonstrate the indispensable role of ADAM10 in S. aureus-inducednecroptosis, and it enhances our knowledge of the role of ADAM10 in S. aureus infection.

Keywords： Host-directed therapy Kaempferol ADAM10 inhibitor Staphylococcus aureus infection Barrier disruption

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Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 237-249 doi: 10.1007/s11684-016-0464-9

Abstract: regenerative capacity because of the active participation of various signaling pathways, including WntThe Wnt and Notch pathways are highly sophisticated and conserved signaling pathways that control multipleIn this regard, Wnt and Notch signaling has gained increased research attention in hair cell regenerationThis review presents the current understanding of the Wnt and Notch signaling pathways in the auditory

Keywords： inner ear cochlea hair cell regeneration Wnt Notch signaling pathways

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Recent advances in special morphologic photocatalysts for NO removal

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 11, doi: 10.1007/s11783-022-1573-0

Abstract: List>

● Systematic information of recent progress in photocatalytic NO_{x i>} removal is provided.

Keywords： NO_xi> removal Photocatalyst Graphene C₃N₄ Bi-based compounds

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lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 317-329 doi: 10.1007/s11684-022-0931-4

Abstract: Moreover, serine/arginine-rich splicing factor 10 (SRSF10i>) knockdown increased the LC3II/LC3IMechanistically, lncR-GAS5 regulated the downstream splicing factor SRSF10i> to impair autophagyin the endothelium, which was reversed by the knockdown of SRSF10i>.SRSF10i>.Thus, miR-193-5p/SRSF10i> may serve as a novel treatment target for atherosclerosis.

Keywords： lncR-GAS5 miR-193-5p splicing factor SRSF10i> autophagy atherogenesis

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Morphology selective construction of

Maher Darwish, Ali Mohammadi, Navid Assi, Samer Abuzerr, Youssef Alahmad

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 4, Pages 561-578 doi: 10.1007/s11705-019-1808-1

Abstract: Controlled growth of Bi WO nanorods with exposed [0 0 1] facets and the fabrication of an Fe O -Bi WOthe influence of various factors on the morphological modulation-photocatalytic behavior of the pure BiConversely, the mechanism of the activity enhancement of -cyclodextrin functionalized Fe O -Bi WO ,

Keywords： βi>-cyclodextrin Bi₂WO₆ shape controlled nanorod sunset yellow

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Novel perspective for urban water resource management:

Lijie Zhou, Hongwu Wang, Zhiqiang Zhang, Jian Zhang, Hongbin Chen, Xuejun Bi, Xiaohu Dai, Siqing Xia,

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 1, doi: 10.1007/s11783-020-1308-z

Abstract: Abstract • 5R (Recover, Reduce, Recycle, Resource and Reuse) approaches to manage urban water. • 5R harvests storm water, gray water and black water in several forms. • 5R offers promise for moving solutions for urban water scarcity in practice. Demand for water is expanding with increases in population, particularly in urban areas in developing countries. Additionally, urban water system needs a novel perspective for upgradation with urbanization. This perspective presents a novel 5R approach for managing urban water resources: Recover (storm water), Reduce (toilet flushing water), Recycle (gray water), Resource (black water), and Reuse (advanced-treated wastewater). The 5R generation incorporates the latest ideas for harvesting storm water, gray water, and black water in its several forms. This paper has briefly demonstrated each R of 5R generation for water treatment and reuse. China has the chance to upgrade its urban water systems according to 5R principles. Already, a demonstration project of 5R generation has been installed in Qingdao International Horticultural Exposition, and Dalian International Convention Center (China) has applied 5R, achieving over 70% water saving. The 5R offers promise for moving solutions for urban water scarcity from “hoped for in the future” to “realistic today”.

Keywords： 5Ri> generation Recover Reduce Recycle Resource Reuse

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Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling

Samuel Chege Gitau,Xuelian Li,Dandan Zhao,Zhenfeng Guo,Haihai Liang,Ming Qian,Lifang Lv,Tianshi Li,Bozhi Xu,Zhiguo Wang,Yong Zhang,Chaoqian Xu,Yanjie Lu,Zhiming Du,Hongli Shan,Baofeng Yang

Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 444-456 doi: 10.1007/s11684-015-0421-z

Abstract: The TAC-operated mice were treated with the human equivalent of low-dose aspirin (10 mg·kg10 nmol·L⁻¹) wastreated with the human equivalent of low (10 or 100 µmol·L⁻¹) and highanterior and posterior walls, the swelling of mitochondria, and the increased surface area in in vivoi> and in vitroi> hypertrophy models.

Keywords： aspirin Akt cardiac hypertrophy GSK-3β Wnt/β-catenin

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ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Frontiers of Medicine 2023, Volume 17, Issue 4, Pages 685-698 doi: 10.1007/s11684-022-0942-1

Abstract: In AML cells, the ACSL5 knockdown inhibited cell growth both in vitroi> and in vivoi>.Mechanistically, the knockdown of ACSL5 suppressed the activation of the Wnt/β-cateninpathway by suppressing the palmitoylation modification of Wnt3a.

Keywords： acute myeloid leukemia acyl-CoA synthetase long chain family member 5 Wnt3a palmitoylation ABT-199

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Bacteria-mediated tumor-targeted delivery of tumstatin (54-132) significantly suppresses tumor growth in mouse model by inhibiting angiogenesis and promoting apoptosis

Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 873-882 doi: 10.1007/s11684-022-0925-2

Abstract: VNP20009, an attenuated Salmonella typhimuriumi> strain, preferentially accumulates in the hypoxicIn this study, a novel Salmonellai>-mediated targeted expression system of tumstatin (VNP-Tum5)with VNP-Tum5 effectively suppressed tumor growth and prolonged survival in the mouse model of B16F10exhibited a higher efficacy in inhibiting the proliferation and inducing the necrosis and apoptosis of B16F10cells in vitroi> and in vivoi> compared with VNP (control).

Keywords： Salmonellai> VNP20009 tumstatin B16F10 melanoma apoptosis angiogenesis

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Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Frontiers of Medicine 2019, Volume 13, Issue 6, Pages 705-712 doi: 10.1007/s11684-019-0703-y

Abstract: Wnt and Notch signaling play crucial roles in the determination of the prosensory domain and in the differentiationHere, we investigated the interactions between Notch and Wnt signaling on the basis of the bidirectionalregulation of Notch1 specifically in Wnt-responsive Lgr5 progenitors during different cochlear developmentWe concluded that the roles of Notch1 in Wnt-responsive Lgr5 cells are unidirectional and stage dependentOur findings improved the understanding of the interactions between Notch and Wnt signaling in cochlear

Keywords： inner ear cochlear Wnt Notch Lgr5 auditory system

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PM₁₀ emissions from industrial coal-fired chain-grate boilers

Xinghua Li, Junzan Han, Lei Duan

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 6, doi: 10.1007/s11783-017-0966-y

Abstract: The PM in the submicron mode for burning with raw coal contributes to 33%±10 % of PM emissions, much

Keywords： coal-fired chain-grate boiler PM₁₀ size distribution particulate emission control devices

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Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Frontiers of Medicine Pages 957-971 doi: 10.1007/s11684-023-0988-8

Abstract: Dynein axonemal heavy chain 10 (DNAH10i>) encodes a subunit of the inner arm dynein heavy chainBased on the common axoneme structure of motile cilia and sperm flagella, DNAH10i> variants areUsing exome sequencing, we identified a novel DNAH10i> homozygous variant (c.589C > T, p.R197W)Immunostaining analysis showed the absence of DNAH10i> and DNALI1i> in the respiratory ciliaSubsequently, animal models of Dnah10i>-knockin mice harboring missense variants and Dnah10

Keywords： DNAH10 mice motile cilia mutation primary ciliary dyskinesia

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Title Author Date Type Operation

MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Journal Article

NES1i>/KLK10i> and hNISi> gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Journal Article

NO hydrogenation to NH over FeCu/TiO catalyst with improved activity

Journal Article

Discovery of Kaempferol, a Novel ADAM10 Inhibitor, as a Potential Treatment for Staphylococcus aureusi> Infection

Tingting Wang, Jianfeng Wang, Xiangzhu Xu, Fan Jiang, Hongfa Lv, Qinghui Qi, Can Zhang, Qianghua Lv, Xuming Deng

Journal Article

Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Journal Article

Recent advances in special morphologic photocatalysts for NO removal

Journal Article

lncR-GAS5 upregulates the splicing factor to impair endothelial autophagy, leading to atherogenesis

Journal Article

Morphology selective construction of

Maher Darwish, Ali Mohammadi, Navid Assi, Samer Abuzerr, Youssef Alahmad

Journal Article

Novel perspective for urban water resource management:

Lijie Zhou, Hongwu Wang, Zhiqiang Zhang, Jian Zhang, Hongbin Chen, Xuejun Bi, Xiaohu Dai, Siqing Xia,

Journal Article

Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling

Samuel Chege Gitau,Xuelian Li,Dandan Zhao,Zhenfeng Guo,Haihai Liang,Ming Qian,Lifang Lv,Tianshi Li,Bozhi Xu,Zhiguo Wang,Yong Zhang,Chaoqian Xu,Yanjie Lu,Zhiming Du,Hongli Shan,Baofeng Yang

Journal Article

ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Journal Article

Bacteria-mediated tumor-targeted delivery of tumstatin (54-132) significantly suppresses tumor growth in mouse model by inhibiting angiogenesis and promoting apoptosis

Journal Article

Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Journal Article

PM₁₀ emissions from industrial coal-fired chain-grate boilers

Xinghua Li, Junzan Han, Lei Duan

Journal Article

Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Journal Article